Membrane currents in isolated frog nerve fibre under voltage clamp conditions
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چکیده
منابع مشابه
Current-voltage relations in the isolated giant axon of the cockroach under voltage-clamp conditions.
Our understanding of the ionic exchanges taking place at the nerve membrane during electrical activity has been greatly increased by the application of the voltageclamp technique. This experimental method consists of the application of a stepwise change in potential to a given area of membrane and the simultaneous measurement of the current flow produced by this given potential gradient. The vo...
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The sucrose-gap method introduced by Stämpfli provides a means for the application of a voltage clamp to the lobster giant axon, which responds to a variety of different experimental procedures in ways quite similar to those reported for the squid axon and frog node. This is particularly true for the behavior of the peak initial current. However, the steady state current shows some differences....
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متن کاملIsolated Frog Nerve Fiber
T HAS BEEN SHOWN that the myelin sheath and the surface membrane at the node of Ranvier of the myelinated nerve fiber behave, to a weak penetrating current, like a condenser with an ohmic resistance connected in parallel (1–5). The absolute values of these capacities and resistances have been estimated already with some accuracy. In order to analyze the process of action potential production at...
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,4BSTRACT TASAKI, I. AND C. S. SPYROPOULOS. Membrane conductance and currentvoltage relation in the squid axon under ‘voltage-clamp.’ &L-The conductance of the squid axon membrane under ‘voltage-clamp’ was measured by superposing a sinusoidal wave upon rectangular clamping voltage pulses. It was possible to determine the time course of the emf of the membrane under ‘voltage-clamp’ on a single p...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1958
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1958.sp006045